2016 is turning out to be a big year for crossovers, and it’s about to get even bigger.

This month, super-powered sisters Blossom, Bubbles and Buttercup of The Powerpuff Girls will team up with Teen Titans GO! as they try to take down Mojo Jojo and “save the world before bedtime.” (If you don’t know who Mojo Jojo is, trust us, this is serious business.) 

As The Powerpuff Girls Executive Producer Nick Jennings told USA Today, “Jump City will never be the same when our little superheroes Blossom, Bubbles and Buttercup meet up with the Teen Titans for the very first time. When these two worlds of superheroes collide, it will surely be something to remember.”

The supercharged mashup comes after The Powerpuff Girls returned to Cartoon Network this spring, and is the latest in the Time Warner family following Batman v Superman: Dawn of Justice. Just last month, The CW announced a mega-crossover bringing together Arrow, DC’s Legends of Tomorrow, The Flash and Supergirl later this year.

"Powerpuff Girls V Teen Titans: Dawn Of Cuteness" is sure to bring a healthy dose of sugar and spice -- plus plenty of Chemical X -- to Teen Titans GO!